Abstract
In this issue of Blood, Kovtunovych et al report the curative effect of a nonmyeloablative bone marrow transplant for anemia and organ dysfunction in heme oxygenase 1 (HO-1)-deficient mice by restoring the ability to detoxify heme through the repopulation of the tissues with wild-type macrophages.1 These findings provide the basis for new therapies for this lethal disorder in children lacking the HO-1 gene (Hmox1).
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1388-1389 |
| Number of pages | 2 |
| Journal | Blood |
| Volume | 124 |
| Issue number | 9 |
| DOIs | |
| State | Published - Aug 28 2014 |
| Externally published | Yes |