TY - JOUR
T1 - Low-fat dairy consumption and reduced risk of hypertension
T2 - The Seguimiento Universidad de Navarra (SUN) cohort
AU - Alonso, Alvaro
AU - Beunza, Juan José
AU - Delgado-Rodríguez, Miguel
AU - Martínez, J. Alfredo
AU - Martínez-González, Miguel Angel
PY - 2005
Y1 - 2005
N2 - Background: Some observational studies have shown a beneficial effect of dairy consumption on blood pressure, especially in overweight and relatively young (<40 y) persons. However, no results from prospective studies conducted in a free-living population exist that show this association in middle-aged adults. Objective: The aim of the present study was to assess whether total, low-fat, and whole-fat dairy consumption was associated prospectively with the risk of hypertension. Design: This was a prospective study conducted in 5880 university graduates in Spain, aged >20 y in 2000 (x̄ age: 37 y), free of hypertension and cardiovascular disease at baseline, and followed-up with mailed questionnaires for a median of 27 mo. Dairy consumption was assessed with a previously validated semiquantitative food-frequency questionnaire. Results: One hundred eighty new cases of hypertension were identified. The hazard ratio of hypertension between extreme quintiles of low-fat dairy product consumption was 0.46 (95% CI: 0.26, 0.84; P for trend = 0.02) after adjustment for the main known risk factors for hypertension and several dietary factors. No significant association between whole-fat dairy products or total calcium intake and incident hypertension was seen. Conclusion: In this Mediterranean cohort, low-fat dairy consumption, but not whole-fat dairy consumption, was associated with a lower risk of incident hypertension.
AB - Background: Some observational studies have shown a beneficial effect of dairy consumption on blood pressure, especially in overweight and relatively young (<40 y) persons. However, no results from prospective studies conducted in a free-living population exist that show this association in middle-aged adults. Objective: The aim of the present study was to assess whether total, low-fat, and whole-fat dairy consumption was associated prospectively with the risk of hypertension. Design: This was a prospective study conducted in 5880 university graduates in Spain, aged >20 y in 2000 (x̄ age: 37 y), free of hypertension and cardiovascular disease at baseline, and followed-up with mailed questionnaires for a median of 27 mo. Dairy consumption was assessed with a previously validated semiquantitative food-frequency questionnaire. Results: One hundred eighty new cases of hypertension were identified. The hazard ratio of hypertension between extreme quintiles of low-fat dairy product consumption was 0.46 (95% CI: 0.26, 0.84; P for trend = 0.02) after adjustment for the main known risk factors for hypertension and several dietary factors. No significant association between whole-fat dairy products or total calcium intake and incident hypertension was seen. Conclusion: In this Mediterranean cohort, low-fat dairy consumption, but not whole-fat dairy consumption, was associated with a lower risk of incident hypertension.
KW - Calcium
KW - Dietary Approaches to Stop Hypertension diet
KW - High blood pressure
KW - Mediterranean diet
KW - Milk
KW - Spain
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U2 - 10.1093/ajcn/82.5.972
DO - 10.1093/ajcn/82.5.972
M3 - Article
C2 - 16280427
AN - SCOPUS:32944474461
SN - 0002-9165
VL - 82
SP - 972
EP - 979
JO - American Journal of Clinical Nutrition
JF - American Journal of Clinical Nutrition
IS - 5
ER -