Abstract
m-Iodosylbenzoic acid selectively oxidizes primary and secondary alcohols to the respective carbonyl compounds in the presence of RuCl3 (0.5 mol%) at room temperature in aqueous acetonitrile. Separation of pure products is conveniently achieved by scavenging any aryl iodide by ion exchange with IRA-900 (hydroxide form) or by simple extraction of the basic aqueous solution with water. The reduced form of the reagent, m-iodobenzoic acid, can be easily recovered from the ion-exchange resin or from the basic aqueous solution by simple acidification with HCl.
Original language | English (US) |
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Pages (from-to) | 563-566 |
Number of pages | 4 |
Journal | Synlett |
Issue number | 4 |
DOIs | |
State | Published - Mar 1 2007 |
Keywords
- Catalysis
- Hypervalent iodine
- Oxidation
- Scavenger
- m-iodosobenzoic acid