Abstract
Colorectal cancer is the third leading cause of cancer deaths in both men and women with 136,830 new cases in the United States estimated to be diagnosed in 2014 [1]. For individuals diagnosed with colorectal cancer, approximately 20% of patients will have metastatic disease at the time of initial diagnosis [2]. Despite the overall incidence of colorectal cancer declining, the number of patients presenting with metastases has remained relatively unchanged. In multiple population-based studies, the incidence of synchronous liver metastases was reported to be 14–18% [3–5]. Similarly, on a population level, the rate of metachronous liver metastases was approximately 12–14% at 3 years [3, 4]. The liver is the most common site of distant colorectal metastases and disease is limited to this site in at least one-third of the patients [6]. Overall, approximately 50% of patients will develop liver metastases at some point during the course of their disease.
Original language | English (US) |
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Title of host publication | Comprehensive Rectal Cancer Care |
Publisher | Springer International Publishing |
Pages | 463-494 |
Number of pages | 32 |
ISBN (Electronic) | 9783319989020 |
ISBN (Print) | 9783319989013 |
DOIs | |
State | Published - Jan 1 2019 |
Bibliographical note
Publisher Copyright:© Springer Nature Switzerland AG 2019.