Modulation of experimental herpes encephalitis-associated neurotoxicity through sulforaphane treatment

Agriculture & Biology

• sulforaphane 92%
• neurotoxicity 74%
• encephalitis 72%
• reactive oxygen species 50%
• astrocytes 49%
• heme oxygenase (biliverdin-producing) 43%
• brain 42%
• neuroglia 33%
• antioxidants 32%
• infection 31%
• neutrophils 19%
• macrophages 18%
• mice 11%
• intraperitoneal injection 10%
• leukocytes 9%
• antioxidant enzymes 9%
• tissues 8%
• cytotoxicity 8%
• neurons 8%
• cell culture 8%
• oxidative stress 7%
• pathogens 5%

Medicine & Life Sciences

• sulforafan 87%
• Herpes Simplex Encephalitis 85%
• Reactive Oxygen Species 48%
• glutathione peroxidase GPX1 46%
• Antioxidants 45%
• Astrocytes 37%
• Heme Oxygenase-1 35%
• Microglia 30%
• Brain 29%
• Virus Diseases 29%
• Neutrophils 15%
• NF-E2-Related Factor 2 14%
• Macrophages 14%
• Human Herpesvirus 1 11%
• Intraperitoneal Injections 9%
• Therapeutics 9%
• Infections 9%
• Free Radicals 9%
• Leukocytes 8%
• Cell Culture Techniques 7%
• Oxidative Stress 7%
• Up-Regulation 7%
• Neurons 6%
• Enzymes 5%
• Mortality 5%
• In Vitro Techniques 4%

Chemical Compounds

• Sulforaphane 100%
• Neurotoxicity 76%
• Antioxidant Agent 46%
• Reactive Oxygen Metabolite 40%
• Heme 24%
• Glutathione 23%
• Peroxidase 23%
• Intraperitoneal 11%
• Clearance 9%
• Oxidative Stress 8%
• Free Radical 6%
• Dioxygen 4%