TY - JOUR
T1 - Multicystic adenomatoid hamartoma of the pancreas
T2 - A hitherto undescribed pancreatic tumor occurring in a 3-year-old boy
AU - Thrall, Michael
AU - Jessurun, Jose
AU - Stelow, Edward B.
AU - Adsay, N. Volkan
AU - Vickers, Selwyn M.
AU - Whitson, Amy K.
AU - Saltzman, Daniel A.
AU - Pambuccian, Stefan E.
PY - 2008/7
Y1 - 2008/7
N2 - This report describes an unusual pancreatic tumor in a 3-year-old boy. He presented with abdominal pain secondary to pancreatitis and was found to have a complex, multicystic lesion within the head of the pancreas. He subsequently underwent a pancreatoduodenectomy. Grossly, the mass was 3 cm, multicystic, and well demarcated. Histologically, there were numerous variably sized, dilated ducts lined by tall columnar mucinous cells surrounded by a stroma that exhibited foci of cellular condensations resembling primitive pancreatic mesenchyme. Acinar and endocrine cells were often seen budding into the ducts forming "ductulo-insular bodies." As a result of its superficial resemblance to Stocker type 2 cystic adenomatoid malformation of the lung, we are proposing the name "multicystic adenomatoid hamartoma" for this lesion.
AB - This report describes an unusual pancreatic tumor in a 3-year-old boy. He presented with abdominal pain secondary to pancreatitis and was found to have a complex, multicystic lesion within the head of the pancreas. He subsequently underwent a pancreatoduodenectomy. Grossly, the mass was 3 cm, multicystic, and well demarcated. Histologically, there were numerous variably sized, dilated ducts lined by tall columnar mucinous cells surrounded by a stroma that exhibited foci of cellular condensations resembling primitive pancreatic mesenchyme. Acinar and endocrine cells were often seen budding into the ducts forming "ductulo-insular bodies." As a result of its superficial resemblance to Stocker type 2 cystic adenomatoid malformation of the lung, we are proposing the name "multicystic adenomatoid hamartoma" for this lesion.
UR - http://www.scopus.com/inward/record.url?scp=53549117455&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=53549117455&partnerID=8YFLogxK
U2 - 10.2350/07-04-0260.1
DO - 10.2350/07-04-0260.1
M3 - Article
C2 - 17990924
AN - SCOPUS:53549117455
SN - 1093-5266
VL - 11
SP - 314
EP - 320
JO - Pediatric and Developmental Pathology
JF - Pediatric and Developmental Pathology
IS - 4
ER -
