NaIO4-Mediated Selective Oxidative Halogenation of Alkenes and Aromatics Using Alkali Metal Halides

Gajanan K. Dewkar; Srinivasarao V. Narina; Arumugam Sudalai

doi:10.1021/ol0358206

NaIO₄-Mediated Selective Oxidative Halogenation of Alkenes and Aromatics Using Alkali Metal Halides

Gajanan K. Dewkar, Srinivasarao V. Narina, Arumugam Sudalai

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Abstract

(Equation presented) NaIO₄ oxidizes alkali metal halides efficiently in aqueous medium to halogenate alkenes and aromatics and produce the corresponding halo derivatives in excellent regio and stereoselectivity. The system also demonstrates the asymmetric version of bromo hydroxylation using β-cyclodextrin complexes, resulting in moderate ee.

Original language	English (US)
Pages (from-to)	4501-4504
Number of pages	4
Journal	Organic Letters
Volume	5
Issue number	23
DOIs	https://doi.org/10.1021/ol0358206
State	Published - Nov 13 2003
Externally published	Yes

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title = "NaIO4-Mediated Selective Oxidative Halogenation of Alkenes and Aromatics Using Alkali Metal Halides",

abstract = "(Equation presented) NaIO4 oxidizes alkali metal halides efficiently in aqueous medium to halogenate alkenes and aromatics and produce the corresponding halo derivatives in excellent regio and stereoselectivity. The system also demonstrates the asymmetric version of bromo hydroxylation using β-cyclodextrin complexes, resulting in moderate ee.",

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journal = "Organic Letters",

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AU - Dewkar, Gajanan K.

AU - Narina, Srinivasarao V.

AU - Sudalai, Arumugam

PY - 2003/11/13

Y1 - 2003/11/13

N2 - (Equation presented) NaIO4 oxidizes alkali metal halides efficiently in aqueous medium to halogenate alkenes and aromatics and produce the corresponding halo derivatives in excellent regio and stereoselectivity. The system also demonstrates the asymmetric version of bromo hydroxylation using β-cyclodextrin complexes, resulting in moderate ee.

AB - (Equation presented) NaIO4 oxidizes alkali metal halides efficiently in aqueous medium to halogenate alkenes and aromatics and produce the corresponding halo derivatives in excellent regio and stereoselectivity. The system also demonstrates the asymmetric version of bromo hydroxylation using β-cyclodextrin complexes, resulting in moderate ee.

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JO - Organic Letters

JF - Organic Letters

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ER -

NaIO₄-Mediated Selective Oxidative Halogenation of Alkenes and Aromatics Using Alkali Metal Halides

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