Nonmotor regions encode path-related information during movements

Macauley S. Breault; Pierre Sacre; Jacob J. Johnson; Matthew Kerr; Matthew D. Johnson; Juan Bulacio; Jorge Gonzalez-Martinez; Sridevi V. Sarma; John T. Gale

doi:10.1109/EMBC.2017.8037571

Nonmotor regions encode path-related information during movements

Macauley S. Breault, Pierre Sacre, Jacob J. Johnson, Matthew Kerr, Matthew D. Johnson, Juan Bulacio, Jorge Gonzalez-Martinez, Sridevi V. Sarma, John T. Gale

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

5 Scopus citations

Abstract

Sensorimotor control and the involvement of motor brain regions has been extensively studied, but the role nonmotor brain regions play during movements has been overlooked. This is particularly due to the difficulty of recording from multiple regions in the brain during motor control. In this study, we utilize stereoelectroencephalography (SEEG) recording techniques to explore the role nonmotor brain areas have on the way we move. Nine humans were implanted with SEEG depth electrodes for clinical purposes, which rendered access to local field potential (LFP) activity in deep and peripheral nonmotor structures. Participants performed fast and slow arm reaching movements using a robotic manipulandum. In this study, we explored whether neural activity in a given nonmotor brain structure correlated to movement path metrics including: path length, path deviation, and path speed. Statistical analysis revealed correlations between averaged neural activity in middle temporal gyrus, supramarginal gyrus, and fusiform gyrus and our path metrics both within and across the subjects. Furthermore, we split trials across subjects into two groups: one group consisted of trials with high values of each path metric and the other with low values. We then found significant differences in LFP power in specific frequency bands (e.g. beta) during movement between each group. These results suggest that nonmotor regions may dynamically encode path-related information during movement.

Original language	English (US)
Title of host publication	2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Subtitle of host publication	Smarter Technology for a Healthier World, EMBC 2017 - Proceedings
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	3339-3342
Number of pages	4
ISBN (Electronic)	9781509028092
DOIs	https://doi.org/10.1109/EMBC.2017.8037571
State	Published - Sep 13 2017
Externally published	Yes
Event	39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2017 - Jeju Island, Korea, Republic of Duration: Jul 11 2017 → Jul 15 2017

Publication series

Name	Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
ISSN (Print)	1557-170X

Other

Other	39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2017
Country/Territory	Korea, Republic of
City	Jeju Island
Period	7/11/17 → 7/15/17

Bibliographical note

Funding Information:
ACKNOWLEDGEMENT This work was supported by a National Science Foundation grant (EFRI-MC3: # 1137237) awarded to S.V.S., J.A.G., J.B., and J.T.G. and the ARCS Foundation awarded to M.S.B.

Publisher Copyright:
© 2017 IEEE.

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10.1109/EMBC.2017.8037571

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Breault, M. S., Sacre, P., Johnson, J. J., Kerr, M., Johnson, M. D., Bulacio, J., Gonzalez-Martinez, J., Sarma, S. V., & Gale, J. T. (2017). Nonmotor regions encode path-related information during movements. In 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Smarter Technology for a Healthier World, EMBC 2017 - Proceedings (pp. 3339-3342). Article 8037571 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/EMBC.2017.8037571

Nonmotor regions encode path-related information during movements. / Breault, Macauley S.; Sacre, Pierre; Johnson, Jacob J. et al.
2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Smarter Technology for a Healthier World, EMBC 2017 - Proceedings. Institute of Electrical and Electronics Engineers Inc., 2017. p. 3339-3342 8037571 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Breault, MS, Sacre, P, Johnson, JJ, Kerr, M, Johnson, MD, Bulacio, J, Gonzalez-Martinez, J, Sarma, SV & Gale, JT 2017, Nonmotor regions encode path-related information during movements. in 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Smarter Technology for a Healthier World, EMBC 2017 - Proceedings., 8037571, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, Institute of Electrical and Electronics Engineers Inc., pp. 3339-3342, 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2017, Jeju Island, Korea, Republic of, 7/11/17. https://doi.org/10.1109/EMBC.2017.8037571

Breault MS, Sacre P, Johnson JJ, Kerr M, Johnson MD, Bulacio J et al. Nonmotor regions encode path-related information during movements. In 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Smarter Technology for a Healthier World, EMBC 2017 - Proceedings. Institute of Electrical and Electronics Engineers Inc. 2017. p. 3339-3342. 8037571. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). doi: 10.1109/EMBC.2017.8037571

Breault, Macauley S. ; Sacre, Pierre ; Johnson, Jacob J. et al. / Nonmotor regions encode path-related information during movements. 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Smarter Technology for a Healthier World, EMBC 2017 - Proceedings. Institute of Electrical and Electronics Engineers Inc., 2017. pp. 3339-3342 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

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Nonmotor regions encode path-related information during movements

Abstract

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Bibliographical note

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