Abstract
The goal of occupational toxicology is to protect worker health. Historically, studies that investigate how workplace conditions affect worker health have provided some of the strongest evidence that exposure to substances in the external environment, such as chemicals, can damage health. Toxicology studies are used to investigate how substances disrupt biological systems to harm health, develop methods to assess the health risks of workplace exposures, and establish occupational exposure limits. Traditional toxicology studies use animal models. New methods for more efficiently predicting and assessing toxicity are being developed based on knowledge of molecular and cellular biology and computational methods.
Original language | English (US) |
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Title of host publication | Encyclopedia of Toxicology, Fourth Edition |
Subtitle of host publication | Volume 1-9 |
Publisher | Elsevier |
Pages | V7-49-V7-56 |
Volume | 7 |
ISBN (Electronic) | 9780128243152 |
DOIs | |
State | Published - Jan 1 2023 |
Bibliographical note
Publisher Copyright:© 2024 Elsevier Inc. All rights reserved.
Keywords
- Adverse outcome pathways
- American Conference of Governmental Industrial Hygienists
- Biomarkers
- Biotransformation
- Health risk assessment
- Molecular toxicology
- Occupational Safety and Health Administration
- Permissible exposure limits
- Threshold limit values
- Toxicogenetics
- Toxicogenomics