TY - JOUR
T1 - Otosclerosis
T2 - etiopathogenesis and histopathology
AU - Cureoglu, Sebahattin
AU - Schachern, Patricia A.
AU - Ferlito, Alfio
AU - Rinaldo, Alessandra
AU - Tsuprun, Vladimir
AU - Paparella, Michael M.
N1 - Funding Information:
This study was supported by Hubbard Broadcasting Foundation, Saint Paul, MN and The Starkey Hearing Foundation Eden Prairie, MN.
Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2006/9
Y1 - 2006/9
N2 - Otosclerosis is a disease of the bony labyrinth manifesting clinically as a progressive conductive hearing loss, a mixed-type hearing loss, or a sensorineural hearing loss. The age of onset of the hearing loss caused by otosclerosis is principally between 15 and 40 years. Although histopathological inner ear changes due to otosclerosis have been very well documented, the true etiopathogenesis of the disease has yet to be described despite intensive research. Both genetic and environmental factors have been implicated, however.
AB - Otosclerosis is a disease of the bony labyrinth manifesting clinically as a progressive conductive hearing loss, a mixed-type hearing loss, or a sensorineural hearing loss. The age of onset of the hearing loss caused by otosclerosis is principally between 15 and 40 years. Although histopathological inner ear changes due to otosclerosis have been very well documented, the true etiopathogenesis of the disease has yet to be described despite intensive research. Both genetic and environmental factors have been implicated, however.
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U2 - 10.1016/j.amjoto.2005.11.001
DO - 10.1016/j.amjoto.2005.11.001
M3 - Review article
C2 - 16935179
AN - SCOPUS:33747759671
SN - 0196-0709
VL - 27
SP - 334
EP - 340
JO - American Journal of Otolaryngology - Head and Neck Medicine and Surgery
JF - American Journal of Otolaryngology - Head and Neck Medicine and Surgery
IS - 5
ER -