Oxytocin as feeding inhibitor: Maintaining homeostasis in consummatory behavior

Pawel K. Olszewski; Anica Klockars; Helgi B. Schiöth; Allen S Levine

doi:10.1016/j.pbb.2010.05.026

Oxytocin as feeding inhibitor: Maintaining homeostasis in consummatory behavior

Pawel K. Olszewski, Anica Klockars, Helgi B. Schiöth, Allen S Levine

Food Science and Nutrition

Research output: Contribution to journal › Review article › peer-review

79 Scopus citations

Abstract

Initial studies showed that the anorexigenic peptide oxytocin (OT) regulates gastric motility, responds to stomach distention and to elevated osmolality, and blocks consumption of toxic foods. Most recently, it has been proposed to act as a mediator of general and carbohydrate-specific satiety and regulator of body weight. In the current review, we discuss the function of OT as a homeostatic inhibitor of consumption, capable of mitigating multiple aspects of ingestive behavior and energy metabolism.

Original language	English (US)
Pages (from-to)	47-54
Number of pages	8
Journal	Pharmacology Biochemistry and Behavior
Volume	97
Issue number	1
DOIs	https://doi.org/10.1016/j.pbb.2010.05.026
State	Published - Nov 2010

Bibliographical note

Funding Information:
The studies were supported by the Swedish Research Counc il (VR), the Swedish Brain Research Foundation and the Novo Nordisk Foundation .

Keywords

Anorexia
Obesity
Paraventricular nucleus of the hypothalamus
Pituitary
Sugar
Taste aversion

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access

10.1016/j.pbb.2010.05.026

OpenUrl availability

Full text

Cite this

@article{2b344004bba24c2282cc3edaf135de0d,

title = "Oxytocin as feeding inhibitor: Maintaining homeostasis in consummatory behavior",

abstract = "Initial studies showed that the anorexigenic peptide oxytocin (OT) regulates gastric motility, responds to stomach distention and to elevated osmolality, and blocks consumption of toxic foods. Most recently, it has been proposed to act as a mediator of general and carbohydrate-specific satiety and regulator of body weight. In the current review, we discuss the function of OT as a homeostatic inhibitor of consumption, capable of mitigating multiple aspects of ingestive behavior and energy metabolism.",

keywords = "Anorexia, Obesity, Paraventricular nucleus of the hypothalamus, Pituitary, Sugar, Taste aversion",

author = "Olszewski, {Pawel K.} and Anica Klockars and Schi{\"o}th, {Helgi B.} and Levine, {Allen S}",

note = "Funding Information: The studies were supported by the Swedish Research Counc il (VR), the Swedish Brain Research Foundation and the Novo Nordisk Foundation .",

year = "2010",

month = nov,

doi = "10.1016/j.pbb.2010.05.026",

language = "English (US)",

volume = "97",

pages = "47--54",

journal = "Pharmacology Biochemistry and Behavior",

issn = "0091-3057",

publisher = "Elsevier Inc.",

number = "1",

}

TY - JOUR

T1 - Oxytocin as feeding inhibitor

T2 - Maintaining homeostasis in consummatory behavior

AU - Olszewski, Pawel K.

AU - Klockars, Anica

AU - Schiöth, Helgi B.

AU - Levine, Allen S

N1 - Funding Information: The studies were supported by the Swedish Research Counc il (VR), the Swedish Brain Research Foundation and the Novo Nordisk Foundation .

PY - 2010/11

Y1 - 2010/11

N2 - Initial studies showed that the anorexigenic peptide oxytocin (OT) regulates gastric motility, responds to stomach distention and to elevated osmolality, and blocks consumption of toxic foods. Most recently, it has been proposed to act as a mediator of general and carbohydrate-specific satiety and regulator of body weight. In the current review, we discuss the function of OT as a homeostatic inhibitor of consumption, capable of mitigating multiple aspects of ingestive behavior and energy metabolism.

AB - Initial studies showed that the anorexigenic peptide oxytocin (OT) regulates gastric motility, responds to stomach distention and to elevated osmolality, and blocks consumption of toxic foods. Most recently, it has been proposed to act as a mediator of general and carbohydrate-specific satiety and regulator of body weight. In the current review, we discuss the function of OT as a homeostatic inhibitor of consumption, capable of mitigating multiple aspects of ingestive behavior and energy metabolism.

KW - Anorexia

KW - Obesity

KW - Paraventricular nucleus of the hypothalamus

KW - Pituitary

KW - Sugar

KW - Taste aversion

UR - http://www.scopus.com/inward/record.url?scp=77957755107&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77957755107&partnerID=8YFLogxK

U2 - 10.1016/j.pbb.2010.05.026

DO - 10.1016/j.pbb.2010.05.026

M3 - Review article

C2 - 20595062

AN - SCOPUS:77957755107

SN - 0091-3057

VL - 97

SP - 47

EP - 54

JO - Pharmacology Biochemistry and Behavior

JF - Pharmacology Biochemistry and Behavior

IS - 1

ER -

Oxytocin as feeding inhibitor: Maintaining homeostasis in consummatory behavior

Abstract

Bibliographical note

Keywords

UN SDGs

Access

OpenUrl availability

Other files and links

Fingerprint

Cite this