Pharmacological evaluation of the long-term effects of xanomeline on the M₁ muscarinic acetylcholine receptor

Chemical Compounds

• Xanomeline 100%
• Parasympathomimetic Agent 61%
• Acetylcholine 52%
• Hydrolysis 6%
• Radioligand 5%
• Culture Media 5%
• Agonist 4%
• Binding Site 3%
• Time 1%

Medicine & Life Sciences

• xanomeline 92%
• Muscarinic Receptors 54%
• Pharmacology 32%
• Hydrolysis 9%
• Muscarinic M1 Receptors 7%
• Allosteric Site 7%
• CHO Cells 5%
• Culture Media 4%
• Binding Sites 3%
• Down-Regulation 3%

Agriculture & Biology

• muscarine receptors 64%
• long term effects 47%
• receptors 33%
• agonists 17%
• hydrolysis 9%
• selectivity (chemistry) 6%
• cells 5%
• washing 5%
• binding sites 5%
• pretreatment 4%
• culture media 4%
• assays 3%