Abstract
A plasmonic nanohole sensor for virus-like particle capture and virucidal drug evaluation is reported. Using a materials-selective surface functionalization scheme, passive immobilization of virus-like particles only within the nanoholes is achieved. The findings demonstrate that a low surface coverage of particles only inside the functionalized nanoholes significantly improves nanoplasmonic sensing performance over conventional nanohole arrays.
Original language | English (US) |
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Pages (from-to) | 1159-1166 |
Number of pages | 8 |
Journal | Small |
Volume | 12 |
Issue number | 9 |
DOIs | |
State | Published - Mar 2 2016 |
Bibliographical note
Publisher Copyright:© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Keywords
- biosensing
- peptides
- plasmonics
- sensors, biosensors, nanohole arrays
- viruses