Polymer-bound triphenylphosphine as traceless reagent for Mitsunobu reactions in combinatorial chemistry: Synthesis of aryl ethers from phenols nad alcohols

Ashok Rao Tunoori; Dinah Dutta; Gunda I. Georg

doi:10.1016/S0040-4039(98)01988-1

Polymer-bound triphenylphosphine as traceless reagent for Mitsunobu reactions in combinatorial chemistry: Synthesis of aryl ethers from phenols nad alcohols

Ashok Rao Tunoori, Dinah Dutta, Gunda I. Georg

Medicinal Chemistry

Research output: Contribution to journal › Article › peer-review

88 Scopus citations

Abstract

The synthesis of aryl ethers from phenols and alcohols using polymer- bound triphenylphosphine and diethyl azodicarboxylate (DEAD) is described. The polymer-bound triphenylphosphines are easily removed by filtration from the reaction products. This method is operationally simple and provides the products with high purity and in good yields.

Original language	English (US)
Pages (from-to)	8751-8754
Number of pages	4
Journal	Tetrahedron Letters
Volume	39
Issue number	48
DOIs	https://doi.org/10.1016/S0040-4039(98)01988-1
State	Published - Nov 26 1998

Bibliographical note

Funding Information:
Acknowledgments: We gratefully acknowledge financial support from the National Cancer Institute (N01-CM-67259), Kansas Technology Enterprise, and the University of Kansas.

Access

10.1016/S0040-4039(98)01988-1

OpenUrl availability

Full text

Cite this

@article{3bac1a3b04e24d56a3c24a87148a9d8c,

title = "Polymer-bound triphenylphosphine as traceless reagent for Mitsunobu reactions in combinatorial chemistry: Synthesis of aryl ethers from phenols nad alcohols",

abstract = "The synthesis of aryl ethers from phenols and alcohols using polymer- bound triphenylphosphine and diethyl azodicarboxylate (DEAD) is described. The polymer-bound triphenylphosphines are easily removed by filtration from the reaction products. This method is operationally simple and provides the products with high purity and in good yields.",

author = "Tunoori, {Ashok Rao} and Dinah Dutta and Georg, {Gunda I.}",

note = "Funding Information: Acknowledgments: We gratefully acknowledge financial support from the National Cancer Institute (N01-CM-67259), Kansas Technology Enterprise, and the University of Kansas.",

year = "1998",

month = nov,

day = "26",

doi = "10.1016/S0040-4039(98)01988-1",

language = "English (US)",

volume = "39",

pages = "8751--8754",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier Limited",

number = "48",

}

TY - JOUR

T1 - Polymer-bound triphenylphosphine as traceless reagent for Mitsunobu reactions in combinatorial chemistry

T2 - Synthesis of aryl ethers from phenols nad alcohols

AU - Tunoori, Ashok Rao

AU - Dutta, Dinah

AU - Georg, Gunda I.

N1 - Funding Information: Acknowledgments: We gratefully acknowledge financial support from the National Cancer Institute (N01-CM-67259), Kansas Technology Enterprise, and the University of Kansas.

PY - 1998/11/26

Y1 - 1998/11/26

N2 - The synthesis of aryl ethers from phenols and alcohols using polymer- bound triphenylphosphine and diethyl azodicarboxylate (DEAD) is described. The polymer-bound triphenylphosphines are easily removed by filtration from the reaction products. This method is operationally simple and provides the products with high purity and in good yields.

AB - The synthesis of aryl ethers from phenols and alcohols using polymer- bound triphenylphosphine and diethyl azodicarboxylate (DEAD) is described. The polymer-bound triphenylphosphines are easily removed by filtration from the reaction products. This method is operationally simple and provides the products with high purity and in good yields.

UR - http://www.scopus.com/inward/record.url?scp=0032569908&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032569908&partnerID=8YFLogxK

U2 - 10.1016/S0040-4039(98)01988-1

DO - 10.1016/S0040-4039(98)01988-1

M3 - Article

AN - SCOPUS:0032569908

SN - 0040-4039

VL - 39

SP - 8751

EP - 8754

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 48

ER -

Polymer-bound triphenylphosphine as traceless reagent for Mitsunobu reactions in combinatorial chemistry: Synthesis of aryl ethers from phenols nad alcohols

Abstract

Bibliographical note

Access

OpenUrl availability

Other files and links

Fingerprint

Cite this