Potential roles of the rodent medial prefrontal cortex in conflict resolution between multiple decision-making systems

Amber E. McLaughlin; Geoffrey W. Diehl; A. David Redish

doi:10.1016/bs.irn.2020.11.009

Potential roles of the rodent medial prefrontal cortex in conflict resolution between multiple decision-making systems

Amber E. McLaughlin, Geoffrey W. Diehl, A. David Redish

Neuroscience

Research output: Chapter in Book/Report/Conference proceeding › Chapter

6 Scopus citations

Abstract

Mammalian decision-making is mediated by the interaction of multiple, neurally and computationally separable decision systems. Having multiple systems requires a mechanism to manage conflict and converge onto the selection of singular actions. A long history of evidence has pointed to the prefrontal cortex as a central component in processing the interactions between distinct decision systems and resolving conflicts among them. In this chapter we review four theories of how that interaction might occur and identify how the medial prefrontal cortex in the rodent may be involved in each theory. We then present experimental predictions implied by the neurobiological data in the context of each theory as a starting point for future investigation of medial prefrontal cortex and decision-making.

Original language	English (US)
Title of host publication	What does Medial Frontal Cortex Signal During Behavior? Insights from Behavioral Neurophysiology
Editors	Adam T. Brockett, Adam T. Brockett, Linda M. Amarante, Mark Laubach, Matthew R. Roesch, Matthew R. Roesch
Publisher	Academic Press Inc.
Pages	249-281
Number of pages	33
ISBN (Print)	9780323853361
DOIs	https://doi.org/10.1016/bs.irn.2020.11.009
State	Published - Jan 2021

Publication series

Name	International Review of Neurobiology
Volume	158
ISSN (Print)	0074-7742
ISSN (Electronic)	2162-5514

Bibliographical note

Publisher Copyright:
© 2021 Elsevier Inc.

Keywords

Anterior cingulate cortex
Central executive
Decision conflict
Decision-making
Deliberation
Infralimbic cortex
Multiple decision systems
Pavlovian
Prelimbic cortex
Procedural

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10.1016/bs.irn.2020.11.009

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McLaughlin, A. E., Diehl, G. W., & Redish, A. D. (2021). Potential roles of the rodent medial prefrontal cortex in conflict resolution between multiple decision-making systems. In A. T. Brockett, A. T. Brockett, L. M. Amarante, M. Laubach, M. R. Roesch, & M. R. Roesch (Eds.), What does Medial Frontal Cortex Signal During Behavior? Insights from Behavioral Neurophysiology (pp. 249-281). (International Review of Neurobiology; Vol. 158). Academic Press Inc.. https://doi.org/10.1016/bs.irn.2020.11.009

Potential roles of the rodent medial prefrontal cortex in conflict resolution between multiple decision-making systems. / McLaughlin, Amber E.; Diehl, Geoffrey W.; Redish, A. David.
What does Medial Frontal Cortex Signal During Behavior? Insights from Behavioral Neurophysiology. ed. / Adam T. Brockett; Adam T. Brockett; Linda M. Amarante; Mark Laubach; Matthew R. Roesch; Matthew R. Roesch. Academic Press Inc., 2021. p. 249-281 (International Review of Neurobiology; Vol. 158).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

McLaughlin, AE, Diehl, GW & Redish, AD 2021, Potential roles of the rodent medial prefrontal cortex in conflict resolution between multiple decision-making systems. in AT Brockett, AT Brockett, LM Amarante, M Laubach, MR Roesch & MR Roesch (eds), What does Medial Frontal Cortex Signal During Behavior? Insights from Behavioral Neurophysiology. International Review of Neurobiology, vol. 158, Academic Press Inc., pp. 249-281. https://doi.org/10.1016/bs.irn.2020.11.009

McLaughlin AE, Diehl GW, Redish AD. Potential roles of the rodent medial prefrontal cortex in conflict resolution between multiple decision-making systems. In Brockett AT, Brockett AT, Amarante LM, Laubach M, Roesch MR, Roesch MR, editors, What does Medial Frontal Cortex Signal During Behavior? Insights from Behavioral Neurophysiology. Academic Press Inc. 2021. p. 249-281. (International Review of Neurobiology). doi: 10.1016/bs.irn.2020.11.009

McLaughlin, Amber E. ; Diehl, Geoffrey W. ; Redish, A. David. / Potential roles of the rodent medial prefrontal cortex in conflict resolution between multiple decision-making systems. What does Medial Frontal Cortex Signal During Behavior? Insights from Behavioral Neurophysiology. editor / Adam T. Brockett ; Adam T. Brockett ; Linda M. Amarante ; Mark Laubach ; Matthew R. Roesch ; Matthew R. Roesch. Academic Press Inc., 2021. pp. 249-281 (International Review of Neurobiology).

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Potential roles of the rodent medial prefrontal cortex in conflict resolution between multiple decision-making systems

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Keywords

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