Prostaglandin E₂ activates cAMP response element-binding protein in glioma cells via a signaling pathway involving PKA-dependent inhibition of ERK

Medicine & Life Sciences

• Cyclic AMP Response Element-Binding Protein 93%
• Extracellular Signal-Regulated MAP Kinases 80%
• Cyclic AMP-Dependent Protein Kinases 76%
• Dinoprostone 71%
• Glioma 68%
• Psychological Inhibition 60%
• Phosphorylation 22%
• Colforsin 15%
• N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide 12%
• Phosphatidylinositol 3-Kinases 9%
• 11-deoxyprostaglandin E1 8%
• Synthetic Prostaglandins 6%
• Wortmannin 5%
• 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 5%
• 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one 5%
• Response Elements 5%
• Growth 4%
• Cyclic AMP 4%
• Neoplasms 1%

Chemical Compounds

• Prostaglandin E2 100%
• Prostaglandin 38%
• Protein 30%
• Forskolin 28%
• LY294002 12%
• Wortmannin 11%
• Phosphotransferase Inhibitor 8%