Proteomic analysis of mucopolysaccharidosis I mouse brain with two-dimensional polyacrylamide gel electrophoresis

Medicine & Life Sciences

• Mucopolysaccharidosis I 100%
• Electrophoresis, Gel, Two-Dimensional 82%
• Proteomics 64%
• Brain 34%
• Neuropathology 22%
• Proteins 22%
• Down-Regulation 21%
• Cytoskeleton 19%
• Synaptic Transmission 18%
• Iduronidase 16%
• Homeostasis 14%
• Biomarkers 13%
• Cytoskeletal Proteins 12%
• Synaptic Vesicles 11%
• Gene Ontology 11%
• Tandem Mass Spectrometry 10%
• Glycosaminoglycans 10%
• Proteome 10%
• Ubiquitin 10%
• Chromatography 9%
• Intellectual Disability 9%
• Cell Death 7%
• Inflammation 5%
• Therapeutics 1%

Chemical Compounds

• Two Dimensional Polyacrylamide Gel Electrophoresis 82%
• Protein 28%
• Biological Marker 18%
• Pharmacological Metabolism 15%
• Glycosaminoglycan 11%
• Cell Death 10%
• Mass Spectrometry 6%