TY - JOUR
T1 - Psychosocial aspects of health-related quality of life and the association with patient-reported bladder symptoms and satisfaction after spinal cord injury
AU - for the Neurogenic Bladder Research Group
AU - Moghalu, Odinachi
AU - Stoffel, John T.
AU - Elliott, Sean
AU - Welk, Blayne
AU - Lenherr, Sara
AU - Herrick, Jennifer
AU - Presson, Angela
AU - Myers, Jeremy
N1 - Publisher Copyright:
© 2021, The Author(s), under exclusive licence to International Spinal Cord Society.
PY - 2021/9
Y1 - 2021/9
N2 - Study design: Prospective, multi-centered, observational. Objectives: To characterize the relationship between psychosocial aspects of health-related quality of life (HRQoL) and patient-reported bladder outcomes. Setting: Multi-institutional sites in the United States, cohort drawn from North America. Methods: We performed a cross-sectional analysis of data collected as part of the multicenter, prospective Neurogenic Bladder Research Group Spinal Cord Injury (SCI) Registry. Outcomes were: Neurogenic Bladder Symptom Score (NBSS), Neurogenic Bladder Symptom Score Satisfaction (NBSS-Satisfaction), and SCI-QoL Bladder Management Difficulties (SCI-QoL Difficulties). Adjusted multiple linear regression models were used with variables including demographic, injury characteristics, and the following psychosocial HRQoL measures; SCI-QoL Pain Interference (Pain), SCI-QoL Independence, and SCI-QoL Positive Affect and Well-being (Positive Affect). Psychosocial variables were sub-divided by tertiles for the analysis. Results: There were 1479 participants, 57% had paraplegia, 60% were men, and 51% managed their bladder with clean intermittent catheterization. On multivariate analysis, higher tertiles of SCI-QoL Pain were associated with worse bladder symptoms, satisfaction, and bladder management difficulties; upper tertile SCI-QoL Pain (NBSS 3.8, p < 0.001; NBSS-satisfaction 0.6, p < 0.001; SCI-QoL Difficulties 2.4, p < 0.001). In contrast, upper tertiles of SCI-QoL Independence and SCI-QoL Positive Affect were associated with improved bladder-related outcomes; upper tertile SCI-QoL Independence (NBSS −2.3, p = 0.03; NBSS-satisfaction −0.4, p < 0.001) and upper tertile SCI-QoL Positive Affect (NBSS −2.8, p < 0.001; NBSS-satisfaction −0.7, p < 0.001; SCI-QoL Difficulties −0.7, p < 0.001). Conclusions: In individuals with SCI, there is an association between psychosocial HRQoL and bladder-related QoL outcomes. Clinician awareness of this relationship can provide insight into optimizing long-term management after SCI.
AB - Study design: Prospective, multi-centered, observational. Objectives: To characterize the relationship between psychosocial aspects of health-related quality of life (HRQoL) and patient-reported bladder outcomes. Setting: Multi-institutional sites in the United States, cohort drawn from North America. Methods: We performed a cross-sectional analysis of data collected as part of the multicenter, prospective Neurogenic Bladder Research Group Spinal Cord Injury (SCI) Registry. Outcomes were: Neurogenic Bladder Symptom Score (NBSS), Neurogenic Bladder Symptom Score Satisfaction (NBSS-Satisfaction), and SCI-QoL Bladder Management Difficulties (SCI-QoL Difficulties). Adjusted multiple linear regression models were used with variables including demographic, injury characteristics, and the following psychosocial HRQoL measures; SCI-QoL Pain Interference (Pain), SCI-QoL Independence, and SCI-QoL Positive Affect and Well-being (Positive Affect). Psychosocial variables were sub-divided by tertiles for the analysis. Results: There were 1479 participants, 57% had paraplegia, 60% were men, and 51% managed their bladder with clean intermittent catheterization. On multivariate analysis, higher tertiles of SCI-QoL Pain were associated with worse bladder symptoms, satisfaction, and bladder management difficulties; upper tertile SCI-QoL Pain (NBSS 3.8, p < 0.001; NBSS-satisfaction 0.6, p < 0.001; SCI-QoL Difficulties 2.4, p < 0.001). In contrast, upper tertiles of SCI-QoL Independence and SCI-QoL Positive Affect were associated with improved bladder-related outcomes; upper tertile SCI-QoL Independence (NBSS −2.3, p = 0.03; NBSS-satisfaction −0.4, p < 0.001) and upper tertile SCI-QoL Positive Affect (NBSS −2.8, p < 0.001; NBSS-satisfaction −0.7, p < 0.001; SCI-QoL Difficulties −0.7, p < 0.001). Conclusions: In individuals with SCI, there is an association between psychosocial HRQoL and bladder-related QoL outcomes. Clinician awareness of this relationship can provide insight into optimizing long-term management after SCI.
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U2 - 10.1038/s41393-020-00609-x
DO - 10.1038/s41393-020-00609-x
M3 - Article
C2 - 33495582
AN - SCOPUS:85099752063
SN - 1362-4393
VL - 59
SP - 987
EP - 996
JO - Spinal Cord
JF - Spinal Cord
IS - 9
ER -