Quantitative nanolc/nsi⁺-hrms method for 1,3-butadiene induced bis-n7-guanine dna-dna cross-links in urine

Medicine & Life Sciences

• 1,3-butadiene 100%
• Guanine 78%
• 3,4-epoxy-1-butene 33%
• diepoxybutane 29%
• N-benzyl-N,N-dimethylamine 29%
• DNA Adducts 11%
• 3,4-epoxy-1,2-butanediol 9%
• Butylene Glycols 8%
• 2,3-butylene glycol 7%
• DNA 7%
• butane 7%
• Vehicle Emissions 6%
• Inhalation Exposure 5%
• Epoxy Compounds 5%
• Rubber 5%
• Laboratory Animals 5%
• Carcinogens 4%
• Plastics 4%
• Smoke 4%
• Tobacco Products 4%
• Inhalation 4%
• Glutathione 3%
• Epidemiologic Studies 3%
• Leukemia 3%
• Creatinine 3%
• Poisons 3%
• Occupational Groups 3%
• Biomarkers 2%
• Proteins 1%
• Neoplasms 1%

Chemical Compounds

• Adduct 47%
• Metabolite 46%
• butane-2,3-diol 29%
• Environmental Substance 23%
• Industrial Substance 22%
• Creatinine 19%
• Smoke 18%
• Biological Marker 14%
• Glutathione 14%
• Epoxide 14%
• Pharmacological Metabolism 12%
• Toxic 12%
• Substitution Reaction 10%

Engineering & Materials Science

• Butadiene 76%
• Metabolites 23%
• Butenes 21%
• DNA Adducts 18%
• DNA 13%
• Carcinogens 6%
• Industrial chemicals 6%
• Butane 5%
• Metabolism 5%
• Smoke 4%
• Substitution reactions 4%
• Animals 4%
• Automobiles 4%
• Proteins 4%
• Rubber 3%
• Plastics 3%