TY - JOUR
T1 - Rac-(6S)-6-Hydroxy-6-{2-[2-(propan-2-ylidene)hydrazinylidene]propyl} indolo[2,1-b]quinazolin-12(6H)-one
AU - Rodstein, Matthew E.
AU - Steffen, Paul D.
AU - Krivogorsky, Bogdana
AU - Grundt, Peter
PY - 2011/10
Y1 - 2011/10
N2 - Thechiraltitlecompound,C 21H 20N 4O 2, crystallizes as a racemic mixture. In the crystal, molecules form centrosymmetric π-overlapping dimers [inter-planar distance = 3.338 (6) Å], which are further connected along the a axis forming centrosymmetric dimers via O-H⋯N hydrogen bonds. C-H⋯O interactions are also observed. The indolo[2,1-b]quinazoline group is somewhat bent, with a small dihedral angle of 6.3 (4)° between the plane of the quinazoline system and the plane of the benzene ring of the indole moiety. The C=N-N=C atoms of the azine group is oriented almost perpendicular [84.1 (2)°] to the mean plane of the quinazoline system.
AB - Thechiraltitlecompound,C 21H 20N 4O 2, crystallizes as a racemic mixture. In the crystal, molecules form centrosymmetric π-overlapping dimers [inter-planar distance = 3.338 (6) Å], which are further connected along the a axis forming centrosymmetric dimers via O-H⋯N hydrogen bonds. C-H⋯O interactions are also observed. The indolo[2,1-b]quinazoline group is somewhat bent, with a small dihedral angle of 6.3 (4)° between the plane of the quinazoline system and the plane of the benzene ring of the indole moiety. The C=N-N=C atoms of the azine group is oriented almost perpendicular [84.1 (2)°] to the mean plane of the quinazoline system.
KW - R factor = 0.062
KW - T = 100 K
KW - mean σ(C-C) = 0.006 Å
KW - single-crystal X-ray study
KW - wR factor = 0.161; data-to-parameter ratio = 11.9
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U2 - 10.1107/S1600536811037408
DO - 10.1107/S1600536811037408
M3 - Article
C2 - 22065467
AN - SCOPUS:80054983934
SN - 1600-5368
VL - 67
SP - o2695-o2696
JO - Acta Crystallographica Section E: Structure Reports Online
JF - Acta Crystallographica Section E: Structure Reports Online
IS - 10
ER -