Rational design and synthesis of novel nucleotide anti-Giardia agents

Dae Hwan Suk; Laurent Bonnac; Christine C. Dykstra; Krzysztof W. Pankiewicz; Steven E. Patterson

doi:10.1016/j.bmcl.2007.01.014

Rational design and synthesis of novel nucleotide anti-Giardia agents

Dae Hwan Suk, Laurent Bonnac, Christine C. Dykstra, Krzysztof W. Pankiewicz, Steven E. Patterson

Center for Drug Design

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Design and synthesis of a novel nucleotide anti-Giardia agent that is micromolar inhibitor of Giardia trophozoite growth in culture is described.

Original language	English (US)
Pages (from-to)	2064-2067
Number of pages	4
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	17
Issue number	7
DOIs	https://doi.org/10.1016/j.bmcl.2007.01.014
State	Published - Apr 1 2007

Keywords

Anti-Giardia drug
Cyst wall synthesis
Giardiasis
Nucleotide

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title = "Rational design and synthesis of novel nucleotide anti-Giardia agents",

abstract = "Design and synthesis of a novel nucleotide anti-Giardia agent that is micromolar inhibitor of Giardia trophozoite growth in culture is described.",

keywords = "Anti-Giardia drug, Cyst wall synthesis, Giardiasis, Nucleotide",

author = "Suk, {Dae Hwan} and Laurent Bonnac and Dykstra, {Christine C.} and Pankiewicz, {Krzysztof W.} and Patterson, {Steven E.}",

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AU - Suk, Dae Hwan

AU - Bonnac, Laurent

AU - Dykstra, Christine C.

AU - Pankiewicz, Krzysztof W.

AU - Patterson, Steven E.

PY - 2007/4/1

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AB - Design and synthesis of a novel nucleotide anti-Giardia agent that is micromolar inhibitor of Giardia trophozoite growth in culture is described.

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KW - Cyst wall synthesis

KW - Giardiasis

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Rational design and synthesis of novel nucleotide anti-Giardia agents

Abstract

Keywords

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