Abstract
Twenty-six patients who had a malignant giant-cell tumor of bone - a sarcoma either juxtaposed to a zone of typical benign giant-cell tumor or occurring at the site of a previously documented benign giant-cell tumor - have been seen at the Mayo Clinic. Of the twenty-six tumors, nineteen were secondary to a previous attempt at local control of a benign giant-cell tumor. All but one of these nineteen patients with a secondary tumor had received therapeutic irradiation four to thirty-nine years earlier. The nature and duration of the symptoms and the sites of predilection of the malignant giant-cell tumors were the same as for benign giant-cell tumor. Fibrosarcoma occurred three times as frequently as osteosarcoma. The best results of treatment of the secondary sarcoma were obtained with early ablation.
Original language | English (US) |
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Pages (from-to) | 1073-1079 |
Number of pages | 7 |
Journal | Journal of Bone and Joint Surgery - Series A |
Volume | 68 |
Issue number | 7 |
DOIs | |
State | Published - Jan 1 1986 |