Sequence-activity mapping via depletion reveals striking mutational tolerance and elucidates functional motifs in Tur1a antimicrobial peptide

Medicine & Life Sciences

• 4-(4-sulfophenylazo)-2-mercuriphenol 100%
• Proline 57%
• Arginine 49%
• Peptides 34%
• Adenosine Monophosphate 29%
• Ribosomes 27%
• Gram-Negative Bacteria 26%
• Anti-Bacterial Agents 17%
• Mutation 15%

Engineering & Materials Science

• Arginine 93%
• Peptides 70%
• Antibiotics 38%
• Bacteria 29%
• Throughput 18%

Chemical Compounds

• Polypeptide Antibiotic Agent 59%
• Arginine 53%
• Proline 27%
• Mutation 22%
• Antimicrobial Agent 18%