TY - JOUR
T1 - Significance of epidermoid formations in the middle ear fetuses and children
AU - Kayhan, Fatma Tulin
AU - Mutlu, Cemil
AU - Schachern, Patricia A.
AU - Le, Chap T.
AU - Paparella, Michael M.
PY - 1997/12
Y1 - 1997/12
N2 - Objective: To determine the incidence, size, and location of epidermoid formations (EFs), which have been suggested to be precursors of congenital cholesteatomas, in temporal bones from fetuses and children. Design: We examined temporal bones from 226 fetuses and children up to the age of 10 years for the incidence, size, and location of EFs. Results: Twenty-five EFs were identified in middle ears of 3 fetuses, 7 neonates, 9 infants, and 2 children aged 2 and 3 years. There was a male-female preponderance of 5:4. Generally, we saw EFs between the anterosuperior edge of the eardrum and the anterior limb of the tympanic ring, but 4 were below the level of the handle of the malleus. Their widths ranged from 25 to 300 μm. Keratinization was not observed in any EF. Contrary to previous reports, we found EFs not only in ears of fetuses, but also in ears of infants and children. Conclusion: Although EFs may persist in some ears, possibly developing into congenital cholesteatomas, our findings do not provide direct support for this concept.
AB - Objective: To determine the incidence, size, and location of epidermoid formations (EFs), which have been suggested to be precursors of congenital cholesteatomas, in temporal bones from fetuses and children. Design: We examined temporal bones from 226 fetuses and children up to the age of 10 years for the incidence, size, and location of EFs. Results: Twenty-five EFs were identified in middle ears of 3 fetuses, 7 neonates, 9 infants, and 2 children aged 2 and 3 years. There was a male-female preponderance of 5:4. Generally, we saw EFs between the anterosuperior edge of the eardrum and the anterior limb of the tympanic ring, but 4 were below the level of the handle of the malleus. Their widths ranged from 25 to 300 μm. Keratinization was not observed in any EF. Contrary to previous reports, we found EFs not only in ears of fetuses, but also in ears of infants and children. Conclusion: Although EFs may persist in some ears, possibly developing into congenital cholesteatomas, our findings do not provide direct support for this concept.
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U2 - 10.1001/archotol.1997.01900120043006
DO - 10.1001/archotol.1997.01900120043006
M3 - Article
C2 - 9413356
AN - SCOPUS:0031437086
SN - 0886-4470
VL - 123
SP - 1293
EP - 1297
JO - Archives of Otolaryngology - Head and Neck Surgery
JF - Archives of Otolaryngology - Head and Neck Surgery
IS - 12
ER -