Abstract
Sinus histiocytosis with massive lymphadenopathy (SHML) is a rare idiopathic proliferative disorder of histiocytes with characteristic morphologic features. We describe a case of SHML occurring in a 14‐yr‐old black male, in whom the diagnosis was made by fine‐needle aspiration of a cervical lymph node. Cytologic features included increased numbers of large histiocytes associated with a polymorphous, cellular background composed of benign lymphocytes, plasma cells, and polymorphonuclear leukocytes. Lymphophagocytosis was a prominent feature. Extranodal involvement of the larynx was documented by surgical biopsy; there was no other extranodal disease. One year after diagnosis, the patient is clinically well, with no residual lymphadenopathy.
Original language | English (US) |
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Pages (from-to) | 513-516 |
Number of pages | 4 |
Journal | Diagnostic Cytopathology |
Volume | 7 |
Issue number | 5 |
DOIs | |
State | Published - Sep 1991 |
Keywords
- Histiocyte
- Larynx
- Lymph node
- Lympho‐phagocytosis
- SHML