Solution Structure of an O⁶-[4-oxo-4-(3-Pyridyl)butyl]guanine Adduct in an 11mer DNA Duplex: Evidence for Formation of a Base Triplex

Medicine & Life Sciences

• Guanine 100%
• Protons 86%
• DNA 47%
• Base Pairing 35%
• Hydrogen Bonding 25%
• O(6)-(4-oxo-4-(3-pyridyl)butyl)guanine 16%
• Tobacco 13%
• Nitrosamines 9%
• pyrimidine 8%
• Cytosine 8%
• purine 8%
• Phosphorus 7%
• Mechanics 7%
• Freezing 7%
• Smoke 6%
• Temperature 5%
• Oxygen 5%
• Ligands 4%
• Neoplasms 4%
• Mutation 3%

Chemical Compounds

• Solution Structure 87%
• Guanine 82%
• Adduct 60%
• Proton 54%
• Nitrosamine 9%
• Hydrogen Bond 8%
• Smoke 7%
• Mechanics 7%
• Cytosine 7%
• Purine 7%
• Pyrimidine 6%
• Mutation 5%
• Phosphorus(.) 5%
• Melting Point 5%
• Chemical Shift 5%
• Dioxygen 3%
• Ligand 3%