Spontaneous cerebrospinal fluid leak due to severe sinonasal granulomatosis with polyangiitis

Varun Sagi; Ethan Kraft; Andrew S. Venteicher; Matthew A. Tyler

doi:10.1016/j.xocr.2022.100435

Spontaneous cerebrospinal fluid leak due to severe sinonasal granulomatosis with polyangiitis

Varun Sagi, Ethan Kraft, Andrew S. Venteicher, Matthew A. Tyler

Research output: Contribution to journal › Article › peer-review

Abstract

Cerebrospinal fluid leak (CSF) due to granulomatosis with polyangiitis (GPA) is a rarely described complication of sinonasal GPA. We report the case of an 80-year-old man found to have a spontaneous CSF leak arising in the context of severe sinonasal GPA. Surgical repair of the cribriform plate defect was performed with no evidence of recurrence at last follow up. Our findings illustrate the importance of early diagnosis and treatment of GPA and highlight some surgical nuances associated with repair of spontaneous CSF leaks in the context of GPA.

Original language	English (US)
Article number	100435
Journal	Otolaryngology Case Reports
Volume	24
DOIs	https://doi.org/10.1016/j.xocr.2022.100435
State	Published - Sep 2022

Bibliographical note

Publisher Copyright:
© 2022

Keywords

Endoscopic sinus surgery
Granulomatosis with polyangiitis
Skull base surgery
Spontaneous cerebrospinal fluid leak

Access

10.1016/j.xocr.2022.100435

OpenUrl availability

Full text

Cite this

@article{c9c2488d9b9641139c06f7d3c580982d,

title = "Spontaneous cerebrospinal fluid leak due to severe sinonasal granulomatosis with polyangiitis",

abstract = "Cerebrospinal fluid leak (CSF) due to granulomatosis with polyangiitis (GPA) is a rarely described complication of sinonasal GPA. We report the case of an 80-year-old man found to have a spontaneous CSF leak arising in the context of severe sinonasal GPA. Surgical repair of the cribriform plate defect was performed with no evidence of recurrence at last follow up. Our findings illustrate the importance of early diagnosis and treatment of GPA and highlight some surgical nuances associated with repair of spontaneous CSF leaks in the context of GPA.",

keywords = "Endoscopic sinus surgery, Granulomatosis with polyangiitis, Skull base surgery, Spontaneous cerebrospinal fluid leak",

author = "Varun Sagi and Ethan Kraft and Venteicher, {Andrew S.} and Tyler, {Matthew A.}",

note = "Publisher Copyright: {\textcopyright} 2022",

year = "2022",

month = sep,

doi = "10.1016/j.xocr.2022.100435",

language = "English (US)",

volume = "24",

journal = "Otolaryngology Case Reports",

issn = "2468-5488",

publisher = "Elsevier Inc.",

}

TY - JOUR

T1 - Spontaneous cerebrospinal fluid leak due to severe sinonasal granulomatosis with polyangiitis

AU - Sagi, Varun

AU - Kraft, Ethan

AU - Venteicher, Andrew S.

AU - Tyler, Matthew A.

PY - 2022/9

Y1 - 2022/9

N2 - Cerebrospinal fluid leak (CSF) due to granulomatosis with polyangiitis (GPA) is a rarely described complication of sinonasal GPA. We report the case of an 80-year-old man found to have a spontaneous CSF leak arising in the context of severe sinonasal GPA. Surgical repair of the cribriform plate defect was performed with no evidence of recurrence at last follow up. Our findings illustrate the importance of early diagnosis and treatment of GPA and highlight some surgical nuances associated with repair of spontaneous CSF leaks in the context of GPA.

AB - Cerebrospinal fluid leak (CSF) due to granulomatosis with polyangiitis (GPA) is a rarely described complication of sinonasal GPA. We report the case of an 80-year-old man found to have a spontaneous CSF leak arising in the context of severe sinonasal GPA. Surgical repair of the cribriform plate defect was performed with no evidence of recurrence at last follow up. Our findings illustrate the importance of early diagnosis and treatment of GPA and highlight some surgical nuances associated with repair of spontaneous CSF leaks in the context of GPA.

KW - Endoscopic sinus surgery

KW - Granulomatosis with polyangiitis

KW - Skull base surgery

KW - Spontaneous cerebrospinal fluid leak

UR - http://www.scopus.com/inward/record.url?scp=85129770485&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85129770485&partnerID=8YFLogxK

U2 - 10.1016/j.xocr.2022.100435

DO - 10.1016/j.xocr.2022.100435

M3 - Article

AN - SCOPUS:85129770485

SN - 2468-5488

VL - 24

JO - Otolaryngology Case Reports

JF - Otolaryngology Case Reports

M1 - 100435

ER -

Spontaneous cerebrospinal fluid leak due to severe sinonasal granulomatosis with polyangiitis

Abstract

Bibliographical note

Keywords

Access

OpenUrl availability

Other files and links

Fingerprint

Cite this