Subcortical intelligence: Caudate volume predicts IQ in healthy adults

Rachael G. Grazioplene; Sephira G. Ryman; Jeremy R. Gray; Aldo Rustichini; Rex E. Jung; Colin G. Deyoung

doi:10.1002/hbm.22710

Subcortical intelligence: Caudate volume predicts IQ in healthy adults

Rachael G. Grazioplene, Sephira G. Ryman, Jeremy R. Gray, Aldo Rustichini, Rex E. Jung, Colin G. Deyoung

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Abstract

This study examined the association between size of the caudate nuclei and intelligence. Based on the central role of the caudate in learning, as well as neuroimaging studies linking greater caudate volume to better attentional function, verbal ability, and dopamine receptor availability, we hypothesized the existence of a positive association between intelligence and caudate volume in three large independent samples of healthy adults (total N=517). Regression of IQ onto bilateral caudate volume controlling for age, sex, and total brain volume indicated a significant positive correlation between caudate volume and intelligence, with a comparable magnitude of effect across each of the three samples. No other subcortical structures were independently associated with IQ, suggesting a specific biological link between caudate morphology and intelligence. Hum Brain Mapp 36:1407-1416, 2015.

Original language	English (US)
Pages (from-to)	1407-1416
Number of pages	10
Journal	Human Brain Mapping
Volume	36
Issue number	4
DOIs	https://doi.org/10.1002/hbm.22710
State	Published - Apr 1 2015

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© 2014 Wiley Periodicals, Inc.

Keywords

Caudate
Dorsal striatum
IQ
Intelligence
Magnetic resonance imaging

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title = "Subcortical intelligence: Caudate volume predicts IQ in healthy adults",

abstract = "This study examined the association between size of the caudate nuclei and intelligence. Based on the central role of the caudate in learning, as well as neuroimaging studies linking greater caudate volume to better attentional function, verbal ability, and dopamine receptor availability, we hypothesized the existence of a positive association between intelligence and caudate volume in three large independent samples of healthy adults (total N=517). Regression of IQ onto bilateral caudate volume controlling for age, sex, and total brain volume indicated a significant positive correlation between caudate volume and intelligence, with a comparable magnitude of effect across each of the three samples. No other subcortical structures were independently associated with IQ, suggesting a specific biological link between caudate morphology and intelligence. Hum Brain Mapp 36:1407-1416, 2015.",

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AU - G. Ryman, Sephira

AU - Gray, Jeremy R.

AU - Rustichini, Aldo

AU - Jung, Rex E.

AU - Deyoung, Colin G.

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Subcortical intelligence: Caudate volume predicts IQ in healthy adults

Abstract

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Keywords

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