Abstract
Tryptanthrin (indolo[2,1-b]quinazoline-6,12-dione) is a natural product which shows significant biological activity as an antibacterial, antiparasitic, and antineoplastic agent. Historically, tryptanthrin has been found as a component of many dyes as well as a constituent of medicinal herbal treatments. This review describes the synthesis of tryptanthrin and some related compounds which also have a quinazoline ring fused to an indolo moiety as a core.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 546-569 |
| Number of pages | 24 |
| Journal | Arkivoc |
| Volume | 2012 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jul 29 2012 |
Keywords
- Alkaloids
- Indoles fused
- Quinazolines fused
- Tryptanthrin