The effect of intracisternally injected ouabain on perilymph electrolyte concentrations

Steven S Juhn; J. Pearce

doi:10.3109/00016487709128855

The effect of intracisternally injected ouabain on perilymph electrolyte concentrations

Steven S Juhn, J. Pearce

Otolaryngology

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

A means for altering the ionic composition of perilymph utilizing the cochlear aqueduct and cerebro-spinal fluid in chinchillas is introduced. A decrease in sodium and an increase in potassium concentration in perilymph was observed after ouabain was injected into cerebrospinal fluid. The time course of changes in the perilymph paralleled the CSF change but with a time lag which had not reached equilibrium within 60 minutes.

Original language	English (US)
Pages (from-to)	349-352
Number of pages	4
Journal	Acta Oto-Laryngologica
Volume	83
Issue number	1-6
DOIs	https://doi.org/10.3109/00016487709128855
State	Published - 1977

Bibliographical note

Funding Information:
This research was supported by a grant from USPHS (NS

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title = "The effect of intracisternally injected ouabain on perilymph electrolyte concentrations",

abstract = "A means for altering the ionic composition of perilymph utilizing the cochlear aqueduct and cerebro-spinal fluid in chinchillas is introduced. A decrease in sodium and an increase in potassium concentration in perilymph was observed after ouabain was injected into cerebrospinal fluid. The time course of changes in the perilymph paralleled the CSF change but with a time lag which had not reached equilibrium within 60 minutes.",

author = "Juhn, {Steven S} and J. Pearce",

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AB - A means for altering the ionic composition of perilymph utilizing the cochlear aqueduct and cerebro-spinal fluid in chinchillas is introduced. A decrease in sodium and an increase in potassium concentration in perilymph was observed after ouabain was injected into cerebrospinal fluid. The time course of changes in the perilymph paralleled the CSF change but with a time lag which had not reached equilibrium within 60 minutes.

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The effect of intracisternally injected ouabain on perilymph electrolyte concentrations

Abstract

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