TY - JOUR
T1 - The genome of the zebra mussel, Dreissena polymorpha
T2 - a resource for comparative genomics, invasion genetics, and biocontrol
AU - McCartney, Michael A.
AU - Auch, Benjamin
AU - Kono, Thomas
AU - Mallez, Sophie
AU - Zhang, Ying
AU - Obille, Angelico
AU - Becker, Aaron
AU - Abrahante, Juan E.
AU - Garbe, John
AU - Badalamenti, Jonathan P.
AU - Herman, Adam
AU - Mangelson, Hayley
AU - Liachko, Ivan
AU - Sullivan, Shawn
AU - Sone, Eli D.
AU - Koren, Sergey
AU - Silverstein, Kevin A.T.
AU - Beckman, Kenneth B.
AU - Gohl, Daryl M.
N1 - Publisher Copyright:
VC The Author(s) 2021.
PY - 2022/2
Y1 - 2022/2
N2 - The zebra mussel, Dreissena polymorpha, continues to spread from its native range in Eurasia to Europe and North America, causing billions of dollars in damage and dramatically altering invaded aquatic ecosystems. Despite these impacts, there are few genomic resources for Dreissena or related bivalves. Although the D. polymorpha genome is highly repetitive, we have used a combination of long-read sequencing and Hi-C-based scaffolding to generate a high-quality chromosome-scale genome assembly. Through comparative analysis and transcriptomics experiments, we have gained insights into processes that likely control the invasive success of zebra mussels, including shell formation, synthesis of byssal threads, and thermal tolerance. We identified multiple intact steamer-like elements, a retrotransposon that has been linked to transmissible cancer in marine clams. We also found that D. polymorpha have an unusual 67 kb mitochondrial genome containing numerous tandem repeats, making it the largest observed in Eumetazoa. Together these findings create a rich resource for invasive species research and control efforts.
AB - The zebra mussel, Dreissena polymorpha, continues to spread from its native range in Eurasia to Europe and North America, causing billions of dollars in damage and dramatically altering invaded aquatic ecosystems. Despite these impacts, there are few genomic resources for Dreissena or related bivalves. Although the D. polymorpha genome is highly repetitive, we have used a combination of long-read sequencing and Hi-C-based scaffolding to generate a high-quality chromosome-scale genome assembly. Through comparative analysis and transcriptomics experiments, we have gained insights into processes that likely control the invasive success of zebra mussels, including shell formation, synthesis of byssal threads, and thermal tolerance. We identified multiple intact steamer-like elements, a retrotransposon that has been linked to transmissible cancer in marine clams. We also found that D. polymorpha have an unusual 67 kb mitochondrial genome containing numerous tandem repeats, making it the largest observed in Eumetazoa. Together these findings create a rich resource for invasive species research and control efforts.
KW - Dreissena polymorpha
KW - Genome
KW - RNA-Seq
KW - Shell formation
KW - Stress response
KW - Thermal tolerance
KW - Zebra mussel
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U2 - 10.1093/g3journal/jkab423
DO - 10.1093/g3journal/jkab423
M3 - Article
C2 - 34897429
AN - SCOPUS:85124419301
SN - 2160-1836
VL - 12
JO - G3: Genes, Genomes, Genetics
JF - G3: Genes, Genomes, Genetics
IS - 2
M1 - jkab423
ER -