Abstract
Since plasmid-encoded antibiotic resistance facilitates the emergence of antibiotic-resistant bacteria, the increasing prevalence of Escherichia coli harboring plasmid-mediated quinolone resistance (PMQR) and extended-spectrum β-lactamase (ESBL) genes is a public health concern. The objective of this study is to investigate the co-existence of PMQR and ESBL genes in E. coli isolates from retail raw chicken in South Korea. Among 67 ESBL-producing E. coli isolates from 40 retail raw chicken, more than half of them carried PMQR genes, including qnrS, aac(6′)-Ib-cr, and oqxAB. The qnrS was predominantly (91.4%) detected in E. coli isolates carrying both PMQR and ESBL. The aac(6′)-Ib-cr was detected in seven ESBL-producing E. coli strains, and 85.7% of the aac(6′)-Ib-cr-positive strains also carried qnrS. Moreover, the strains co-harboring qnrS and aac(6′)-Ib-cr exhibited increased resistance to ciprofloxacin and kanamycin. These results demonstrate that PMQR genes are frequently detected in ESBL-producing E. coli isolates from retail raw chicken in South Korea.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 739-743 |
| Number of pages | 5 |
| Journal | Food Science and Biotechnology |
| Volume | 31 |
| Issue number | 6 |
| DOIs | |
| State | Published - Jun 2022 |
Bibliographical note
Funding Information:HP and JK were supported by the BK21 Plus Program of the Department of Agricultural Biotechnology, Seoul National University, Seoul, Korea. BJ is supported by Global Food Ventures through MnDRIVE (Minnesota’s Discovery, Research, and InnoVation Economy). This research was supported by a grant 19162MFDS037 from the Ministry of Food and Drug Safety in 2021.
Publisher Copyright:
© 2022, The Korean Society of Food Science and Technology.
Keywords
- Antibiotic resistance in food
- Escherichia coli, plasmid-mediated quinolone resistance (PMQR)
- Extended-spectrum β-lactamase (ESBL)
- Plasmid-mediated antibiotic resistance
PubMed: MeSH publication types
- Journal Article