Therapeutic interventions targeting the nitric oxide system: Current and potential uses in obstetrics, bone disease and erectile dysfunction

Marianne K.O. Grant; Esam E El-Fakahany

doi:10.1016/j.lfs.2003.08.029

Therapeutic interventions targeting the nitric oxide system: Current and potential uses in obstetrics, bone disease and erectile dysfunction

Marianne K.O. Grant, Esam E El-Fakahany

Experimental and Clinical Pharmacology

Research output: Contribution to journal › Short survey › peer-review

7 Scopus citations

Abstract

Nitric oxide is involved in a countless number of physiological processes and is known to have cytoprotective as well as cytotoxic effects. Increased knowledge about the multifaceted role of nitric oxide in a variety of disease states has led to the design of multiple treatment strategies involving the nitric oxide system. The current review focuses on recent research advances in the fields of obstetrics, bone disease and erectile dysfunction that have led to current or potential future therapies involving nitric oxide.

Original language	English (US)
Pages (from-to)	1701-1721
Number of pages	21
Journal	Life Sciences
Volume	74
Issue number	14
DOIs	https://doi.org/10.1016/j.lfs.2003.08.029
State	Published - Feb 20 2004

Bibliographical note

Funding Information:
The authors gratefully acknowledge Drs. Jean and John Oberpriller and Mr. David Oberpriller for their helpful comments. This work was supported by NIH grant NS25743.

Keywords

Cervical ripening
Erectile dysfunction
Nitric oxide
Osteoporosis
Preterm labor
Rheumatoid arthritis

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title = "Therapeutic interventions targeting the nitric oxide system: Current and potential uses in obstetrics, bone disease and erectile dysfunction",

abstract = "Nitric oxide is involved in a countless number of physiological processes and is known to have cytoprotective as well as cytotoxic effects. Increased knowledge about the multifaceted role of nitric oxide in a variety of disease states has led to the design of multiple treatment strategies involving the nitric oxide system. The current review focuses on recent research advances in the fields of obstetrics, bone disease and erectile dysfunction that have led to current or potential future therapies involving nitric oxide.",

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AU - El-Fakahany, Esam E

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AB - Nitric oxide is involved in a countless number of physiological processes and is known to have cytoprotective as well as cytotoxic effects. Increased knowledge about the multifaceted role of nitric oxide in a variety of disease states has led to the design of multiple treatment strategies involving the nitric oxide system. The current review focuses on recent research advances in the fields of obstetrics, bone disease and erectile dysfunction that have led to current or potential future therapies involving nitric oxide.

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KW - Osteoporosis

KW - Preterm labor

KW - Rheumatoid arthritis

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Therapeutic interventions targeting the nitric oxide system: Current and potential uses in obstetrics, bone disease and erectile dysfunction

Abstract

Bibliographical note

Keywords

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