Thermal response of superparamagnetic particles suspended in liquid and solid media

Pengyun Zeng; Timothy L. Kline; Jian ping Wang; Timothy Scott Wiedmann

doi:10.1016/j.jmmm.2008.09.032

Thermal response of superparamagnetic particles suspended in liquid and solid media

Pengyun Zeng, Timothy L. Kline, Jian ping Wang, Timothy Scott Wiedmann

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

The purpose of this study was to explore the properties of coated superparamagnetic nanoparticles (SPNs) specifically for their use in thermal-responsive drug delivery systems. Coated, magnetite SPNs were prepared and dispersed in cyclohexane or cetyl alcohol, a solid lipid at the physiological temperatures of 37 °C. The induced temperature change as a function of SPN concentration and external magnetic field and frequency was consistent with theoretical predictions. SPNs dispersed in a solid lipid matrix underwent heating and the associated melting occurred at a temperature suitable for a thermal-responsive drug delivery system.

Original language	English (US)
Pages (from-to)	373-376
Number of pages	4
Journal	Journal of Magnetism and Magnetic Materials
Volume	321
Issue number	5
DOIs	https://doi.org/10.1016/j.jmmm.2008.09.032
State	Published - Mar 2009

Bibliographical note

Funding Information:
This work was supported by NSF BME 0730825 and the Medical Device Center, University of Minnesota, Minneapolis, MN. We acknowledge Professor Chun Wang for the use of Dynamic Light Scattering.

Keywords

Cetyl alcohol
Cyclohexane
Magnetic nanoparticles
Thermal release

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title = "Thermal response of superparamagnetic particles suspended in liquid and solid media",

abstract = "The purpose of this study was to explore the properties of coated superparamagnetic nanoparticles (SPNs) specifically for their use in thermal-responsive drug delivery systems. Coated, magnetite SPNs were prepared and dispersed in cyclohexane or cetyl alcohol, a solid lipid at the physiological temperatures of 37 °C. The induced temperature change as a function of SPN concentration and external magnetic field and frequency was consistent with theoretical predictions. SPNs dispersed in a solid lipid matrix underwent heating and the associated melting occurred at a temperature suitable for a thermal-responsive drug delivery system.",

keywords = "Cetyl alcohol, Cyclohexane, Magnetic nanoparticles, Thermal release",

author = "Pengyun Zeng and Kline, {Timothy L.} and Wang, {Jian ping} and Wiedmann, {Timothy Scott}",

note = "Funding Information: This work was supported by NSF BME 0730825 and the Medical Device Center, University of Minnesota, Minneapolis, MN. We acknowledge Professor Chun Wang for the use of Dynamic Light Scattering. ",

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T1 - Thermal response of superparamagnetic particles suspended in liquid and solid media

AU - Zeng, Pengyun

AU - Kline, Timothy L.

AU - Wang, Jian ping

AU - Wiedmann, Timothy Scott

N1 - Funding Information: This work was supported by NSF BME 0730825 and the Medical Device Center, University of Minnesota, Minneapolis, MN. We acknowledge Professor Chun Wang for the use of Dynamic Light Scattering.

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N2 - The purpose of this study was to explore the properties of coated superparamagnetic nanoparticles (SPNs) specifically for their use in thermal-responsive drug delivery systems. Coated, magnetite SPNs were prepared and dispersed in cyclohexane or cetyl alcohol, a solid lipid at the physiological temperatures of 37 °C. The induced temperature change as a function of SPN concentration and external magnetic field and frequency was consistent with theoretical predictions. SPNs dispersed in a solid lipid matrix underwent heating and the associated melting occurred at a temperature suitable for a thermal-responsive drug delivery system.

AB - The purpose of this study was to explore the properties of coated superparamagnetic nanoparticles (SPNs) specifically for their use in thermal-responsive drug delivery systems. Coated, magnetite SPNs were prepared and dispersed in cyclohexane or cetyl alcohol, a solid lipid at the physiological temperatures of 37 °C. The induced temperature change as a function of SPN concentration and external magnetic field and frequency was consistent with theoretical predictions. SPNs dispersed in a solid lipid matrix underwent heating and the associated melting occurred at a temperature suitable for a thermal-responsive drug delivery system.

KW - Cetyl alcohol

KW - Cyclohexane

KW - Magnetic nanoparticles

KW - Thermal release

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JO - Journal of Magnetism and Magnetic Materials

JF - Journal of Magnetism and Magnetic Materials

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Thermal response of superparamagnetic particles suspended in liquid and solid media

Abstract

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