Three-component synthesis of cyclic enaminones via ketene cyclization

Hajime Seki; Gunda I. Georg

doi:10.1021/ol200358h

Three-component synthesis of cyclic enaminones via ketene cyclization

Hajime Seki, Gunda I. Georg

Medicinal Chemistry

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

Chemical equations presented. Cyclic six-membered enaminones were synthesized from three components (bromodiazoacetone, primary amine, and alkyne) in high yields via aza-Michael addition, Wolff rearrangement, and nucleophilic ketene cyclization.

Original language	English (US)
Pages (from-to)	2147-2149
Number of pages	3
Journal	Organic Letters
Volume	13
Issue number	9
DOIs	https://doi.org/10.1021/ol200358h
State	Published - May 6 2011

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title = "Three-component synthesis of cyclic enaminones via ketene cyclization",

abstract = "Chemical equations presented. Cyclic six-membered enaminones were synthesized from three components (bromodiazoacetone, primary amine, and alkyne) in high yields via aza-Michael addition, Wolff rearrangement, and nucleophilic ketene cyclization.",

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AU - Seki, Hajime

AU - Georg, Gunda I.

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N2 - Chemical equations presented. Cyclic six-membered enaminones were synthesized from three components (bromodiazoacetone, primary amine, and alkyne) in high yields via aza-Michael addition, Wolff rearrangement, and nucleophilic ketene cyclization.

AB - Chemical equations presented. Cyclic six-membered enaminones were synthesized from three components (bromodiazoacetone, primary amine, and alkyne) in high yields via aza-Michael addition, Wolff rearrangement, and nucleophilic ketene cyclization.

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Three-component synthesis of cyclic enaminones via ketene cyclization

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