Treatment of heterozygous type II hyperlipidemia by partial ileal bypass in a pediatric population

Marshall Z. Schwartz; Richard L. Varco; Henry Buchwald

doi:10.1016/S0022-3468(76)80197-2

Treatment of heterozygous type II hyperlipidemia by partial ileal bypass in a pediatric population

Marshall Z. Schwartz, Richard L. Varco, Henry Buchwald

Surgery

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Abstract

Nine patients underwent partial ileal bypass as management for heterozygous type II hyperlipidemia. The average age of this group was 12.5 yr. Follow-up has ranged from 1 to 6 yr. The growth and development of these children proceeded normally. The overall average serum cholesterol reduction was 33% when compared to the preoperative but postdietary control value. Side effects of the procedure include transient diarrhea and inability to absorb vitamin B₁₂, requiring periodic parenteral administration. Partial ileal bypass has been shown to be an effective and obligatory method of treatment of hypercholesterolemia in children.

Original language	English (US)
Pages (from-to)	411-418
Number of pages	8
Journal	Journal of Pediatric Surgery
Volume	11
Issue number	3
DOIs	https://doi.org/10.1016/S0022-3468(76)80197-2
State	Published - Jun 1976

Bibliographical note

Funding Information:
From the Departments of Surgery, Biomedical Engineering, and the Cardiovascular and Thoracic Surgery Training Program, University of Minnesota Hospitals, Minneapolis, Minn. Presented before the 24th Annual Meeting of the American Academy of Pediatrics, Surgical Section, Washington, D.C., October 19 21, 1975. Supported by USP United States Public Service Grant HL-11901. Address for reprints: Marshall Schwartz, M.D., Box 290, University of Minnesota Hospitals, Minneapolis, Minn. 55455. 9 1976 by Grune & Stratton, Inc.

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abstract = "Nine patients underwent partial ileal bypass as management for heterozygous type II hyperlipidemia. The average age of this group was 12.5 yr. Follow-up has ranged from 1 to 6 yr. The growth and development of these children proceeded normally. The overall average serum cholesterol reduction was 33% when compared to the preoperative but postdietary control value. Side effects of the procedure include transient diarrhea and inability to absorb vitamin B12, requiring periodic parenteral administration. Partial ileal bypass has been shown to be an effective and obligatory method of treatment of hypercholesterolemia in children.",

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Treatment of heterozygous type II hyperlipidemia by partial ileal bypass in a pediatric population

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