Abstract
We recently compared results of fecal microbiota transplantation (FMT) in patients with refractory, recurrent Clostridium difficile infection (rCDI), with and without underlying inflammatory bowel disease (IBD). Here we extend this cohort and analyze outcomes in greater detail by subtype of IBD. We find that FMT is generally effective in breaking the cycle of CDI recurrence, but its effects on overall IBD progression are much less predictable. We discuss several challenges intrinsic to this complex clinical situation and outline the next steps that can address these challenges going forward.
Original language | English (US) |
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Pages (from-to) | 303-309 |
Number of pages | 7 |
Journal | Gut microbes |
Volume | 8 |
Issue number | 3 |
DOIs | |
State | Published - May 2017 |
Bibliographical note
Publisher Copyright:© 2017 Taylor & Francis
Keywords
- Crohn's disease
- clostridium difficile
- fecal microbiota transplantation
- inflammatory bowel disease
- ulcerative colitis