Use of dupilumab for atopic dermatitis in young transplant patients—A case series of 3 patients

Maritza V. Steele; Rachit Gupta; Sheilagh Maguiness; Christina Boull

doi:10.1111/pde.15280

Use of dupilumab for atopic dermatitis in young transplant patients—A case series of 3 patients

Maritza V. Steele, Rachit Gupta, Sheilagh Maguiness, Christina Boull

Dermatology

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1 Scopus citations

Abstract

Patients who undergo solid organ transplantation are at an increased risk of developing atopic dermatitis, potentially due to long-term use of calcineurin inhibitors which results in a shift towards the Th2 immune response. The effectiveness and safety of dupilumab for atopic dermatitis in posttransplant patients is not established. Previous reports of dupilumab use in posttransplant patients have been in adult patients. In this series, we report three young posttransplant patients treated successfully with dupilumab.

Original language	English (US)
Pages (from-to)	897-899
Number of pages	3
Journal	Pediatric Dermatology
Volume	40
Issue number	5
DOIs	https://doi.org/10.1111/pde.15280
State	Published - Sep 1 2023

Bibliographical note

Publisher Copyright:
© 2023 The Authors. Pediatric Dermatology published by Wiley Periodicals LLC.

Keywords

auto-islet cell transplantation
dupilumab
immunosuppression
renal transplant
transplant
transplant rejection

PubMed: MeSH publication types

Case Reports

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abstract = "Patients who undergo solid organ transplantation are at an increased risk of developing atopic dermatitis, potentially due to long-term use of calcineurin inhibitors which results in a shift towards the Th2 immune response. The effectiveness and safety of dupilumab for atopic dermatitis in posttransplant patients is not established. Previous reports of dupilumab use in posttransplant patients have been in adult patients. In this series, we report three young posttransplant patients treated successfully with dupilumab.",

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Use of dupilumab for atopic dermatitis in young transplant patients—A case series of 3 patients

Abstract

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Keywords

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