Velocity encoding and velocity compensation for multi-spoke RF excitation

Simon Schmidt, Sebastian Flassbeck, Peter Bachert, Mark E. Ladd, Sebastian Schmitter

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Purpose: To investigate velocity encoded and velocity compensated variants of multi-spoke RF pulses that can be used for flip-angle homogenization at ultra-high fields (UHF). Attention is paid to the velocity encoding for each individual spoke pulse and to displacement artifacts that arise in Fourier transform imaging in the presence of flow. Theory and methods: A gradient waveform design for multi-spoke excitation providing an algorithm for minimal TE was proposed that allows two different encodings. Such schemes were compared to an encoding approach that applies an established scheme to multi-spoke excitations. The impact on image quality and quantitative velocity maps was evaluated in phantoms using single- and two-spoke excitations. Additional validation measurements were obtained in-vivo at 7 T. Results: Phantom experiments showed that keeping the first gradient moment constant for all k-space lines eliminates any displacements in phase-encoding and slice-selection direction for all spoke pulses but leads to artifacts for non-zero velocity components along readout direction. Introducing variable but well-defined first gradient moments in the phase-encoding direction creates displacements along the velocity vector and thus minimizes velocity-induced geometrical distortions. Phase-resolved mean volume flow in the ascending and descending aorta obtained from two-spoke excitation showed excellent agreement with single-spoke excitation over the cardiac cycle (mean difference 0.8 ± 16.2 ml/s). Conclusions: The use of single- and multi-spoke RF pulses for flow quantification at 7 T with controlled displacement artifacts has been successfully demonstrated. The presented techniques form the basis for correct velocity quantification and compensation not only for conventional but also for multi-spoke RF pulses allowing in-plane B1 + homogenization using parallel transmission at UHF.

Original languageEnglish (US)
Pages (from-to)69-85
Number of pages17
JournalMagnetic Resonance Imaging
Volume66
DOIs
StatePublished - Feb 2020

Bibliographical note

Funding Information:
The research leading to these results has received funding from the European Research Council under the European Union Seventh Framework Programme (FP/2007–2013)/ERC Grant Agreement n. 291903 MRexcite.

Publisher Copyright:
© 2019 Elsevier Inc.

Keywords

  • 4D-flow
  • Displacement artifact
  • Flow quantification
  • Multi-spoke RF pulses
  • Parallel transmit
  • RF shimming

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