Prospects of food-derived α-glucosidase inhibitors in the management of diabetes

Ruth T. Boachie, Prince G. Boakye, George A. Annor, Chibuike C. Udenigwe

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Food-derived compounds have been explored as active components for the management of type 2 diabetes mellitus. One of the primary bioactivity mechanisms is through the inhibition of α-glucosidase, which is involved in the release of glucose from dietary carbohydrates during digestion in the gastrointestinal tract. This chapter discusses the regulation of carbohydrate digestion during normal and abnormal conditions, and the α-glucosidase inhibitory activity of food-derived compounds, including peptides, phenolic compounds, terpenoids, and nonstarch polysaccharides.

Original languageEnglish (US)
Title of host publicationFood Structure and Functionality
PublisherElsevier
Pages219-233
Number of pages15
ISBN (Electronic)9780128214534
DOIs
StatePublished - Jan 1 2020

Bibliographical note

Publisher Copyright:
© 2021 Elsevier Inc.

Keywords

  • Nonstarch polysaccharides
  • Peptides
  • Phenolic compounds
  • Terpenoids
  • Type 2 diabetes mellitus
  • α-Glucosidase
  • α-glucosidase inhibitor

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